Sappho and Alcaeus is an oil-on-canvas painting by the Dutch-British artist Lawrence Alma-Tadema, from 1881.

It depicts a concert in the late 7th century BC, with the poet Alcaeus of Mytilene playing the kithara.

In the audience is fellow Lesbos poet Sappho, accompanied by several of her female friends.

The painting illustrates a passage by the poet Hermesianax, recorded by Athenaeus in his Deipnosophistae ("The Philosophers' Banquet"), book 13, page 598.

The location, with tiers of white marble seating, is based on the Theatre of Dionysus in Athens, but Alma-Tadema replaced the original inscribed names of Athenians with the names of Sappho's friends.