Sara also appeared in a Turner Network Television live-action feature film and TV series of the same name and she was portrayed by Yancy Butler.
As one of the current hosts of the Witchblade, Sara has been granted many unique abilities, including the power and ability to heal herself, to create (often very revealing) armor over her skin (as the Witchblade tends to rip away all of her clothes), to shoot energy blasts, to extend razor sharp tendrils and even winged flight.
While on an undercover case at the Rialto Theater, both she and her partner, Michael Yee (named Danny Woo in the TV series), were mortally wounded.
While Sara lay dying, the Witchblade made his choice to include her in the long line of women that he has shared his power with.
Since then, she has seen many things she never knew existed, fought creatures that have no place on Earth, and longed for the days of a typical NYPD detective.
In the comics recently, Sara has been through a grueling ordeal fighting off a giant demon (a false "god" summoned by a group of priests), in the midst of which her partner, Jake McCarthy, was left wounded.
When she was due to give birth, the father of her child was revealed – it was Jackie Estacado, who, possessed by the Darkness itself, was driven to seek out and have sex with Sara's comatose body, and, with Jackie's body used for the necessary biology, leading to the conception of their baby – a child to upset the balance between the dark and light.
He confronted Sara, demanding that she either resign as a detective or give up the Witchblade if she doesn't want to be exposed.
She is likewise a skilled hand-to-hand combatant and markswoman, able to hold her own in a gunfight as well as against physical opponents noticeably larger and stronger than herself.
As the host of the Witchblade, she was granted a vast array of supernatural abilities, such as; forming various weapons (swords, other stabbing weapons, hooks, chains, shields), jump to heights higher than most humans could jump to, generate a full body armor in order to protect herself, increase her strength to abnormal levels that exceed 500 pounds (should the situation arise, she can also form wings allowing flight), shoot energy blasts from the gauntlet, fire projectile darts, and whip-like grapples to attack or to climb.
For offence, the witchblade can assume the form of a gauntlet, with a wrist-mounted retractable blade, and, one-step forward, even as a Pata-esq weapon.
According to former wielder, Joan of Arc, during the Periculum, when Sara asks her what the Witchblade is, she answers that it is a branch from the Tree of good and evil; in another episode, it is described as the product of divine alchemy.
It was also revealed in the last episode of the series that the Witchblade will not and cannot bring death to anyone that has wielded it, able to only maim, disfigure and cause pain.
Former wielders of the Witchblade include Saren (a fictional Artemis-esq wood nymph goddess of Sumerian religion, and who was the uninterested object of Gilgamesh's unrequited lust, and was hunted by Enkidu), Cathain (based on Scáthach of Irish & Scottish legend, and lover of Conchobar), Joan of Arc, Florence Nightingale (although she was not of the wielder's bloodline), and Elizabeth Brontë (an American spy in WWII), along with unidentified Egyptian, Babylonian, Indian, Chinese, Japanese and Celtic woman (all with the same face as Sara Pezzini) throughout human history.
It is revealed that Sara was not only adopted, but stolen from her birth mother when she was a baby she also had a sister that appeared in the series once, named Karen Bronte.
In the second season, he meets Aras, a woman genetically identical to Sara (a biological cousin of hers from about five generations back), and they share a kiss.