Sarah entered Lloyd's Register in 1797 with T. Reeves, master, Dickson, owner, and trade Liverpool–Africa.

1st enslaving voyage (1797–1798): Captain Thomas Rives acquired a letter of marque on 17 July 1797.

[2] Captain Rives sailed from Liverpool on 9 August and started gathering slaves at Bonny on 4 October.

Sarah sailed from Africa 21 November, and arrived at Montego Bay on 22 January 1798.

[a] Dolben's Act apparently resulted in some reduction in the numbers of captives carried per vessel, and possibly in mortality, though the evidence is ambiguous.

3rd enslaving voyage (1799–1800): Captain John Brelsford (or Brailsford) sailed from Liverpool on 11 October 1799.

She sailed from Kingston on 25 April and arrived back at Liverpool 25 June.

[9] 6th enslaving voyage (1802–1803): Captain Thomas Cannell sailed from Liverpool on 21 August 1802.

[2] He left Liverpool on 13 September with 55 crew members on Sarah's 7th enslaving voyage.

[15] Lloyd's List reported on 4 May 1804 that Sarah, Cannell, master, had been captured and carried into Guadeloupe.

[18] However, absent detailed vessel-by-vessel histories, it is not always clear whether a homeward-bound vessel was a Guineaman or not.