She then made two voyages as a slave ship in the triangular trade in enslaved people.

Sarah entered Lloyd's Register (LR), in 1803 with John Sellars, master, R. Kitchen, owner, and trade Liverpool–Africa.

[a]Ville de Lyons, of some 400 tons (bm), was carrying a cargo of tea, pepper, indigo, etc., valued at about £26,000.

Sarah purchased captives at the Cameroons and arrived at Kingston, Jamaica, on 11 September 1804.

[8] Captain John McLune sailed Sarah from Liverpool on 26 October 1805 on her 3rd enslaving voyage.

[11] Four days later Lloyd's List reported that L'Hermite's squadron of the French Navy had captured Sarah, Otway, Lord Nelson, Mary, Adams, master, and Nelson, Meath, master, off the coast of Africa.