Following Animal House, she appeared as Maggie O'Hooligan in Caddyshack (1980).
Holcomb had been cast in Jaws 2 (1978), but was one of several teenaged actors let go as that film went through many script revisions early in production.
[1] Holcomb struggled with mental illness and drug abuse.
She was institutionalized for a period before stabilizing and retiring from the entertainment industry and avoiding publicity.
[2] The character of Dorri Lawrence in the film Stateside, an actress who suffers from schizophrenia, is partly based on Holcomb.