Treem was born in Boston, Massachusetts, to a mother who works as a consultant/angel investor and advisor to start-ups and to a father who is a pediatric gastroenterologist.
[7] Having started her career in theater, Treem's most recent stage production When We Were Young and Unafraid premiered in the summer of 2014, which starred Cherry Jones and was directed by Pam MacKinnon.
A Feminine Ending premiered at Playwrights Horizons and went on to be produced at South Coast Repertory and Portland Center Stage, among others.
Set in Montauk, New York, the show examines the psychological effects of an affair between a married waitress and a teacher who spends his summer at his in-laws' estate in the small coastal town.
[9] In November 2019, Treem signed a multi-year deal with Fox 21 television studios to create and produce series for their network, cable and streaming platforms.
[11] Treem wrote an essay about the reality of "having it all" as a working mother for Red Magazine in 2017, in a post that eventually went viral.
[16] Treem has forged ongoing creative relationships with actresses like Zoe Kazan (who knew each other from Yale) and Alison Pill.