The station stop was established in 1869 when the Santa Clara and Pajaro Valley Railroad extended its line to Sargent.

Prior to 1769, the site was inhabited by approximately 2,700 Amah Mutsun Ohlone Indigenous peoples who lived in villages along the Pajaro River before the arrival of Spanish colonizers who settled in Alta California.

most of the over 500 members of the Amah Mutsun band are descendants of the native people who were later baptized at Mission San Juan Bautista.

[1] Spanish explorers led by the military officer Juan Bautista de Anza and Pedro Font (missionary) first passed through the Santa Clara Valley area in 1776.

[9] By 1945, Southern Pacific Railroad Coast Line timetables indicated that stops at Sargent station were made on signal for passengers traveling to Los Angeles and other destinations.