It runs from Highway 4, five kilometres (3 mi) south of Rosetown, to Highway 16, four kilometres (2 mi) southeast of Bredenbury.

[1] The Outlook Bridge carries Highway 15 across the South Saskatchewan River.

Major communities serviced by Highway 15 are Outlook and Melville.

The highway parallels the main line of the Canadian National Railway between Nokomis and Melville.

[citation needed] From west to east:[2] Media related to Saskatchewan Highway 15 at Wikimedia Commons