Highway 220 heads west to Last Mountain Lake and Rowan's Ravine Provincial Park.

After Duval, it resumes its northerly routing passing by the communities of Cymric, Govan, Hatfield, Nokomis,[8] Lockwood, and Drake en route to Highway 16 and Lanigan.

Less than 3 kilometres (1.9 mi) before Gurnsey, Highway 20 leaves the concurrency with 16 and resumes its northerly routing.

Along this stretch, the highway provides access to Burr and Bay Trail and skirts around the western shore of Humboldt Lake.

Along this final leg, the highway provides access to the communities of Fulda, Pilger, Middle Lake, St. Benedict, Tarnopol, and Crystal Springs; intersects Highways 756, 669, 777, 41, 320, and 778; and passes by the lakes of Burton, Deadmoose, Houghton, Lucien, Basin, Dixon, and Jumping.