Highway 335 is a provincial highway in the Canadian province of Saskatchewan.

It runs from Highway 6 near Gronlid to Highway 23 west of Arborfield.

It is about 51 kilometres (32 mi) long.

[1] Highway 335 passes near the communities of Gronlid, Armley, and Nicklen, and also intersects Highway 681 and Highway 35.

The intersection with Highway 35 at Amrley was the scene of a 2018 collision resulting in 16 fatalities of the Humboldt Broncos, a team of the Saskatchewan Junior Hockey League.