Sathyamurthi Perumal Temple in Thirumayam, a panchayat town in the South Indian state of Tamil Nadu, is dedicated to the Hindu god Vishnu.

Constructed in the Dravidian style of architecture, the temple is glorified in the Nalayira Divya Prabandham, the early medieval Tamil canon of the Alvar saints from the 6th–9th centuries CE.

It is one of the 108 Divya Desams dedicated to Vishnu, who is worshipped as Sathyamurthi Perumal and his consort Lakshmi as Ujeevana Thayar.

Four daily rituals and many yearly festivals are held at the temple, of which the car festival during the Tamil month of Vaikasi (April - May), Krishna Jayanti during Avani (August - September) and Adi Puram during July - August being the most prominent.

Once, Adishesha, the serpent-mount of Vishnu, wanted to convert his guna (quality) from tamas (darkness) to satvik (purity).

He has also compared the images of the temple to that of Vijayalaya Choleeswaram in Narthamalai, built by Muttaraiyar kings during the same period.

The main statue of Sathyamurthi Perumal approximately seven feet in height, is standing on a rock, along with his wives.

The wall behind the presiding deity has images of Garuda, Chitragupta, Markandeya, Brahma, the devas, the vasus, and the kinnaras.

[8][9] Sathyamurthi Perumal temple is revered in Nalayira Divya Prabhandam, the 7th–9th century Vaishnava canon, by Thirumangai Alvar.

During the 18th and 19th centuries, the temple finds mention in several works like 108 Tirupathi Anthathi by Divya Kavi Pillai Perumal Aiyangar.

In modern times, the temple priests perform the pooja (rituals) during festivals and on a daily basis.

As at other Vishnu temples of Tamil Nadu, the priests belong to the Vaishnavaite community, from the Brahmin class.

Four daily rituals are performed at various times of the day and many yearly festivals are held at the temple, of which the car festival during the Tamil month of Vaikasi (April - May), Krishna Jayanti during Avani (August - September) and Adi Puram during July - August being the most prominent.