[16] In 2019, it established a political alliance with the Freedom, Unity and Solidarity Party (PLUS) led by former technocratic Prime Minister Dacian Cioloș which it eventually absorbed in 2021.

USR continued the political project Save Bucharest Union (Romanian: Uniunea Salvați Bucureștiul) at the national level, established on 1 July 2015.

[29] On 11 October 2021, Klaus Iohannis nominated USR leader and former technocratic Prime Minister Dacian Cioloș to form a new government.

[36] On 1 July 2022, it was announced that Allen Coliban lost the internal elections for being the contender of Cătălin Drulă for the leadership of the party.

[40][41][42] On 14 December 2023, Save Romania Union, Force of the Right and the People's Movement Party officially announced the creation of a right-wing electoral alliance to contest in the 2024 elections.

[50] The alliance's chosen slogan used to be Fără hoție ajungem departe, meaning "Without thievery we go far" and referring to the existing corruption in Romania.

[52] On 15 August 2020, members of the USR and PLUS held an online congress to decide whether to formally unite the two parties or not, with 84.65% of the participants voting in favor of a merger.

[56][57] On 5 October 2016, the Save Romania Union (USR) had officially launched its political programme,[58] with nine chapters on the following areas: transparency, industry, agriculture, education, culture, health, infrastructure, environmental protection, and foreign policy.

[59] USR advocates for maximum transparency, industrialization with modern means, support for small farmers, education reform, a new paradigm in the cultural field, granting 6% of GDP for Health, construction of highways and infrastructure in collaboration with European partners, environmental protection in particular by stopping deforestation as well as close cooperation with the European Union (EU), NATO, and support for accession in these international organizations for neighbouring Republic of Moldova and Ukraine.

[60] The president of the USR, Nicușor Dan, said that the program is still in public debate, and could be improved in the nearest future, according to the society's suggestions and recommendations.

[61] In October 2016, the USR declared the public endorsement for then Prime Minister Dacian Cioloș for a new mandate, following the December's parliamentary elections.

[69] Another source labelled the party as "a diverse group of activists, academics and people from business and the arts, which grew out of a Save Bucharest movement to protect the city’s historic buildings.

[72] He compared the party with Emmanuel Macron's Renaissance, while mentioning that the key difference between the two is that USR predominantly consists of people who have not been involved in politics before.

During the 2017–2019 Romanian protests, USR was against the modifications to the justice laws initiated by the government coalition PSD-ALDE and requested the rejection of OUG 13.

In 2018, USR helped and endorsed the initiators of Fără Penali în Funcții Publice ("No Convicts in Public Office") civic campaign, whose objective is to bar the persons convicted to final imprisonment sentences for intentional offences from being elected to local government, the Chamber of Deputies, the Senate, or the office of President of Romania by amending the Article 37 of the Romanian Constitution[77] (which regulates the nomination rules).

[78] USR advocates for the Party of Action and Solidarity (PAS) led by Maia Sandu,[79] and highlights the European path of Moldova.

[80] At the June 2018 elections for the Chișinău mayoralty, USR endorsed the candidate of the pro-European forces, more specifically Andrei Năstase.

"[16] USR was the only parliamentary party in Romania that was against the constitutional referendum, proposed by Coaliția pentru Familie (CpF) and endorsed by the Romanian Orthodox Church.

[84][85] USR considered the referendum a way to divide the Romanian people and to distract the attention from the real issues Romania is facing, such as corruption.

At the 42nd session of the UNESCO World Heritage Committee, held in Manama, Bahrain, the government's representative, Ștefan Răzvan Rab, state secretary of the Ministry of Culture, in Bahrain, on June 24 to July 4, asked for postponement on behalf of Romania including the Roșia Montană Mining Cultural Landscape in the World Heritage List until the completion of the judicial dispute with Gabriel Resources.

[88] In May 2019, the party stated[89] that it would take part in the new liberal group in the European Parliament that includes France's La République En Marche!, named Renew Europe in June 2019.