Scaphiophryne spinosa is a species of frog in the family Microhylidae.

It is endemic to eastern Madagascar.

It has been considered synonym of Scaphiophryne marmorata, but a revision in 2002 restored its species status.

[1][3] It inhabits pristine rainforests, swampy forests, forest edges, and degraded forests; it is absent from very open areas.

Habitat loss is a threat to this species.