On January 29, 2013, she founded the Jesse Lewis Choose Love Movement to provide Character Social Emotional Development programs to schools and other organizations free of cost.

Their programs are now taught in over 10,000 schools, in all 50 states and in over 120 countries, serving over 3 million children annually.

[13] Lewis has explained that the fundamental basis for their programming spawned from a message Jesse had left on a chalkboard at their home that phonetically spelled out the words of: Nurturing, Healing, Love.

[14][15][16][17][18] Lewis's non-profit provides programming that can help educators and students "to choose love, handle adversity, and manage their emotions".

[21] Lewis is often asked by press to weigh in on topics of school shootings and their root causes.