The distribution of Schistosoma spindale includes Sri Lanka, India, Bangladesh, Thailand,[1] Malaysia, and Laos.

[5] Surveillance for cattle schistosomiasis is generally inadequate and the literature is limited, but some idea of the problem can be gained from past small scale studies.

[5][7] More recently, in Kerala South India, prevalences have been reported up to 57.3% in cattle, 50% in water buffalo (Bubalus bubalis) and 4.7% in goats.

Thus, it was as low as 10–30% by faecal examination (again low if egg detection method is employed and high if hatching method is followed) with as high as 80–95% by examining mesentery of the animals for live schistosomes during post mortem.

[9][page needed] Schistosoma spindale was found causing an outbreak in cattle in Maharashtra leading to heavy mortality with symptoms similar to Rinder pest.