The specific epithet refers to Isalo National Park, near where the species was identified.

[3] Schizolaena isaloensis grows as a tree up to 10 metres (33 ft) tall.

[4] Schizolaena isaloensis is known only from the south central regions of Ihorombe and Atsimo-Andrefana,[2] specifically within[5] and just beyond the southern limit of Isalo National Park and near the RN7 road.

[3] Its habitat is the central region's Tapia woodlands which are often severely degraded; the recorded specimens occurred in open grassland.

[3] Schizolaena isaloensis has been found in very low numbers – at most 50 mature individuals.