The site began life as the Daresbury Laboratory later forming a joint venture and adding the Cockcroft Institute, Innovation Centre, Vanguard House, Hartree Centre, Techspace One, Techspace Two, Violet, Campus Technology Hub and ITAC.

In 2012 it was given enterprise zone status and renamed Sci-Tech Daresbury.

[2] The Cockcroft Institute is an international centre for Accelerator Science and Technology (AST) in the UK.

The Institute is located in a purpose-built building on the Daresbury campus, and in centres in each of the participating universities.

The Hartree Centre is a high performance computing, data analytics and artificial intelligence (AI) research facility focused on industry-led challenges.