[3][4] The show's initial grant was projected to expire in 2014, and in response, on September 12, 2013, SciShow joined the viewer-funding site Subbable, created in part by Green.

Similarly, SciShow Psych rotated hosting between Hank Green, Brit Garner, and Anthony Brown.

[13] Several different scientific fields are covered by SciShow, including chemistry, physics, biology, zoology, geology, geography, entomology, botany, meteorology, astronomy, medicine, psychology, anthropology, math and computer science.

[19] A second spin-off, SciShow Kids, launched in March 2015 to specialize in delivering science topics to children.

[21][22] A third spinoff channel was announced in February 2017, SciShow Psych, which debuted in March 2017, specializing in psychology and neuroscience.

[24] A podcast, SciShow Tangents, was launched in November 2018; it features entertaining exchanges of scientific facts among many of the shows' staffers, and is directed at a mature audience.

[26] It consists of a panel format where Hank Green, Ceri Riley, Stefan Chin, and Sam Schultz share facts about science on a weekly theme; each episode has multiple segments, several of which are competitive.