On 20 September Captain J. Saunders sailed her from England for Mauritius under a license from the British East India Company.

[3] On 9 September 1831 Captain W. Saunders sailed her from Britain to Van Diemen's Land.

Science, Saunders, master, foundered off Cape Horn, Chile on 21 June after having been badly damaged by heavy seas at 56°S 125°W / 56°S 125°W / -56; -125.

The American South Sea whaler Warren rescued the crew.

[a] Science was on a voyage from Van Diemen's Land to London.