Located in McLean, it is bordered by Virginia State Route 193 to its south, Interstate 495 to its east and the Potomac River to its north.

It encompasses 336 acres (136 ha) of woodland with its namesake, Scott's Run, flowing through its west side.

Scott's Run originates in nearby Tysons Corner and enters the Potomac on the northwest side of the preserve.

After Burling's death in October 1966, his descendants sold the property to Miller & Smith Associates (MSA) to avoid its tax burdens.

After a lengthy debate between citizens, the Virginia Governor, several U.S. senators, developers, and local organizations, voters opted to raise their taxes in a referendum on July 14, 1970.