Scotts Run is a 1.89 mi (3.04 km) long 2nd order tributary to Big Sandy Creek in Fayette County, Pennsylvania, United States.

Washington,[2] and then flows southwest to join Big Sandy Creek about 3 miles north-northeast of Elliottsville.

[3] Scotts Run drains 1.28 square miles (3.3 km2) of area, receives about 50.8 in/year of precipitation, has a wetness index of 302.71, and is about 96% forested.

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