Scranton is a town in Florence County, South Carolina, United States.

[6] U.S. Route 52 passes through the town, leading north 20 miles (32 km) to Florence, the county seat, and south 3 miles (5 km) to Lake City.

According to the United States Census Bureau, the town of Scranton has a total area of 0.85 square miles (2.2 km2), all land.

There were 347 housing units at an average density of 417.0 per square mile (161.0/km2).

24.5% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older.