[5][6] Most of the flowers do not appear at the top of the main stem but are produced along the length of side branches that grow from the leaf axils.

The principal phytochemicals are polyphenols in the leaves, stems, and roots of some Scutellaria species, including baicalin, baicalein, wogonin, and oroxylin A.

[citation needed] Its extracts are used in herbal medicine intended as a mild sedative and sleep promoter.

[15] In 1773, Scutellaria lateriflora became a common treatment in North America for the hysteria and hydrophobia caused by rabies.

[16] Skullcap products have been analyzed, with some adulterated by Teucrium canadense or T. chamaedrys, also known as germander, which contains potentially hepatotoxic diterpenes.