Sean Ryan Christopher Spence (born June 7, 1990) is an American college football coach and former professional linebacker.

He played college football at the University of Miami, where he was named 2008 Atlantic Coast Conference Defensive Rookie of the Year.

At Miami Northwestern High School, Spence was part of the 2007 national championship team as chosen by USA Today.

[1] His teammates included Lavonte David, Marcus Forston, Jacory Harris, Tommy Streeter, and Brandon Washington.

[8][9] Three weeks after being taken off of the PUP list, the Steelers placed Spence on injured reserve, ending his injury-ridden 2013 season.

Spence, who missed one game and didn't finish two due to hamstring injuries, had 37 tackles and a sack as the Steelers completed the 2015 regular season with a 10–6 mark.

[11] On March 16, 2016, the Tennessee Titans signed Spence to a one-year, $2.5 million contract, reuniting him with former Steelers defensive coordinator Dick LeBeau.