While Seaton Village shares several characteristics with the Annex (notably its architecture and popularity with University of Toronto students), it is often perceived as a quieter, family-oriented neighbourhood.

Nearly the entirety of Seaton Village's portion of Bloor Street is occupied by a Korean ethnic enclave known as Koreatown.

Before the influx of Korean immigrants in the 1980s, this section of Bloor Street was populated by people from Central and South America.

The ten most common languages spoken at home, after English, are: Seaton Village is the former home of Canadian poet and children's author Dennis Lee, Oscar-winning (for Chicago) sound engineer David Lee (no relation, now deceased), and sociologist Barry Wellman.

It is the current home of musician Charles Spearin, professor and author Jordan Peterson, and songwriter/performer Nancy White.

Seaton Village was also where Meghan Markle, UK's Duchess of Sussex, lived in a rented house at 10 Yarmouth Gardens while filming the TV series Suits.