Sebastian River High School is a co-educational International Baccalaureate high school in Sebastian, Florida.

It opened August 1994 and is operated by the School District of Indian River County.

Situated on 6.5 acres (2.6 ha) of land, Sebastian River High School is constructed around a central courtyard with a bell tower as its focal point.

It also has 2 separate classroom buildings for the Junior Reserve Officers' Training Corps (JROTC).

In 2002, a new freshman wing, the V Wing, was added, bringing the number of classrooms to over 140 and making Sebastian River High School the second largest high school in Indian River County.