Sebhat Ephrem (Tigrinya: ስብሓት ኤፍረም; born 1951) is an Eritrean military officer and politician who is the Minister of Energy and Mines for Eritrea.

His father was a Protestant-educated hospital administrator and Sebhat attended the Evangelical Lutheran School in Asmara, Eritrea.

He became the General Staff of the EPLA in 1986 and was credited as the leading strategist of the victories at Afabet, Massawa and Dekemhare.

After leaving the military in June 1992, he returned to the army in May 1995 with the rank of general and was appointed and confirmed as Minister of Defense.

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