Second Lady of Ghana or Second Gentleman of Ghana is the title given to the spouse of the vice-president of the Republic of Ghana.

[1][2] The current second gentleman is Edmund Opoku-Agyemang, who has held that position since 7 January 2025 when his wife Jane Naana Opoku-Agyemang was sworn into office.

They are not officially given salaries but the Ghanaian first and second lady and gentlemen are both given clothing allowances to serve as initiatives to be comfortable enough to advocate the country through material forms of culture.

They usually undertake social programmes and philanthropic activities especially in relation to kids and women.

This Ghana-related article is a stub.