[2][3] There is no scientific evidence to support the belief that cycling the seeds actually regulates the hormonal rhythm,[4] but the practice is probably harmless.
[6] The seed cycling diet suggests sesame or sunflower seeds to boost progesterone at this time, ground up to increase the surface area for absorption of the essential fatty acids, minerals, and other nutrients.
There is currently a lack of solid scientific evidence that supports seed rotating between the phases of the menstrual cycle or the Moon directly impacts hormonal disorders.
[4] The Cut quotes dietitian Abby Langer as stating that food is not medicine, but that seed cycling might be "a worthwhile component of a treatment plan" for a hormonal imbalance, warning that seed cycling recipes using primrose oil could interact dangerously with anticoagulants and anaesthetics.
[9] Shape magazine notes that the seeds could possibly help regulate hormones, given their phytoestrogen content, but quotes Melinda Ring of the Osher Center for Integrative Medicine at Northwestern University in Chicago as stating that evidence is lacking, that the outcomes are unpredictable, and that she has seen women whose cycles became "more irregular" after taking phytoestrogens.