Seitlhamo was the son of Motswasele I, kgosi of the Kwena people.
[1] Kgabo Tebele described Seitlhamo as a patient ruler, in contrast with his predecessor.
Reportedly, the attack took place after Seitlhamo's junior son Mooketse covertly met with the Ngwaketse chief and told him when Dithejane would be undefended.
[1] Legwale's succession was challenged by another of Seitlhamo's sons, Tshosa.
[2] Legwale's successor, Sietlhamo's son Maleke, led an attack against the Bangwaketse to avenge Seitlhamo's death.