Tshosa was a son of the Kwena kgosi Seitlhamo, born in the third house, and he was the junior brother of Legwale and Maleke.
While he was regent of the Bakwena, Tshosa was responsible for defending the tribe from two raids by the Bangwaketse, first in Mantsho and then in Kgomphata.
[2] Tshosa's regency ended in 1807 when he passed the role of chief to his nephew and the next in line, Motswasele II.
[2] The Kwena tribe fractured after Motswasele's death, and Tshosa led one faction to Borithe, Molepolole, and then Dithubaruba.
After returning to the land of the Kwena, he reunited his faction with that of Motswasele's son, Sechele I, and they went to Diruthe.