[2] Her family life is unknown, but she is sometimes credited as the daughter of Neith and Khnum, making her a sister to Sobek and Apep.

Although Serket does not appear to have had any temples, she had a sizable number of priests in many communities.

One of the most dangerous species of scorpion, the deathstalker (Leiurus quinquestriatus) resides in North Africa and its sting may kill, so Serket was considered a highly important goddess and sometimes she was considered by pharaohs to be their patron.

As the guard of one of the canopic jars and a protector, Serket gained a strong association with Neith, Isis, and Nephthys, who also performed similar functions.

The appearance of a waterscorpion must have made it be associated with the scorpion, therefore the use of the goddess for curing scorpion stings and other venomous creatures or maybe exactly because she "causes to breathe", not for the physical similarities of the creatures.