Separation Anxiety is an American television game show hosted by Iliza Shlesinger.

An unsuspecting couple is brought to a studio in Atlanta, where they think they're playing together on an Internet game show for a top prize of $2,500.

The in-studio player will select the categories that their partner is playing in the fake Internet game.

The real prizes are 100 times the dollar amounts shown in the fake game (so the first $10 question is really worth $1,000).

During the game, the in-studio player gets several opportunities, called "Mind Melds", to earn bonus prizes for predicting what their partner did during hidden-camera segments shot after the players were separated but before the fake game taping began.