The type specimen was collected off the coast of South Africa and is deposited at the Muséum National d'Histoire Naturelle in Paris.

[9] A huge threat to Sepia tuberculata, as well as many other Cephalopods, is ocean acidification due to anthropogenic carbon dioxide emissions.

Changes in the 33chemistry of seawater has been found to increase calcification rates in a relative of S. tuberculata, S. officinalis.

This exhibition of food preference is shown very early in life for cuttlefish and suggests that choosing to prey on shrimp is an innate behavior.

Adhesion is a common occurrence that is used by many plants and animals including Cephalopods, the class to which all Cuttlefish belong.

[13] Sepia are one taxa of cephalopods that produce a chemical substance to be used for adhesion; the use of this secretion varies depending on each specific animal.