The Prophet 2000 is a sampler keyboard manufactured by Dave Smith's Sequential Circuits (SCI) and released in 1985.

Using the technology developed for the 2000, Sequential also produced the Prophet 2002, a rack-mounted version of the 2000, and the Studio 440, a drum machine and sequencer that used a similar sampler at its core.

Despite their technological limitations, early digital samplers like the Prophet 2000 are noted for their warm audio quality as a result of using analog VCFs and VCAs.

Engineer Chris Meyer corrected this issue for the Prophet VS, the first digital synthesizer given the green light by Sequential founder Dave Smith.

The 440 also made it easier to access the full 512 kilowords of available memory by allowing the creation of samples as long as 12 seconds.

[3] Like the Prophet 3000, the Studio 440—and many of Sequential's products—lost sales due to the brand loyalty demanded by its competitors, including Akai Professional, Roland Corporation, and Korg.