Sergei Mikhailovich Smirnov (Russian: Серге́й Миха́йлович Смирно́в, born October 12, 1950) is a retired Russian intelligence officer whose career ended with a seventeen-year stint as First Deputy Director of the Federal Security Service (FSB).

While not a personal friend of Vladimir Putin, he was a member of the Leningrad security clique.

When Putin was made director of the FSB in 1998, Patrushev became his deputy and Smirnov moved to Moscow.

From January 5, 2001, to June 2003, he was the Chief of the Saint Petersburg and Leningrad Oblast FSB Directorate.

In October 2020, Smirnov retired quietly in an apparent dismissal by Vladimir Putin.