Chejfec published eighteen books, including novels, essays, short stories, and a poetry collection.

From 1990 to 2005 he lived in Venezuela, where he published Nueva sociedad, a journal of politics, culture and the social sciences.

He most recently lived in New York City and held the position of Distinguished Writer in Residence in the M.F.A.

His novels usually feature a slow-paced narration that interweaves a minimal plot with reflection.

Memory, political violence, and Jewish-Argentine culture and history are some of the recurring themes in his work.