Serpierite (Ca(Cu,Zn)4(SO4)2(OH)6·3H2O) is a rare, sky-blue coloured hydrated sulfate mineral, often found as a post-mining product.

[2] It was discovered in 1881 and named by Alfred Des Cloizeaux in honour of Giovanni Battista Serpieri [el].

[2] Serpierite is a hydrated sulfate with the formula Ca(Cu,Zn)4(SO4)2(OH)6·3H2O[5] with molar mass 644.32 g[3] and calculated density 3.08 g/cm3.

It occurs as tufts and crusted aggregates of lath-like or bladed crystals typically less than 1 mm long.

[8][2][4] Sources differ widely about the hardness of serpierite, giving values varying between 2[2] and 4.

[3][4][9] The type locality is the Serpieri Mine, Kamariza, Lavrion District, Greece,[2] and type material is conserved at the National Museum of Natural History, Paris, France, reference 73.38, 78.226.

[7] Serpierite is a secondary mineral found in altered smelter slags and oxidised sulfide veins.

[3][7] At the type locality it is associated with smithsonite[2] and it has also been found associated with devilline, posnjakite, ktenasite, linarite, langite, brochantite, wroewolfeite, namuwite, schulenbergite, hydrozincite, malachite and gypsum.