The Serra do Divisor National Park is divided between the municipalities of Rodrigues Alves (13.45%), Porto Walter (26.99%), Marechal Thaumaturgo (4.73%), Mâncio Lima (31.71%) and Cruzeiro do Sul (23.12%) in the state of Acre.

[2] The park is bounded to the west by the border with Peru, which runs along the Serra Divisor mountain range.

[5] In 2013, Rainforest Trust launched a campaign to fund the establishment of another national park in the same area on the Peruvian side of the border.

Separating the two basins of Rio Ucayali (Peru) and Juruá (Brazil), the Park shelters main sources of Jurua 's left margin affluent.

It is structured in four main hill massifs (Serras da Jaquirana, do Moa, do Jurua-Mirim & do Rio Branco), separated by flat plains and valleys of the corresponding affluent of the Juruá basin.

Margins of the lower section of the Juruá and Moa rivers are regularly to permanently inundated, having many lakes, igapós and igarapés.

Vegetation: Rapid ecological assessment survey in 1991 characterised 10 forest types within the Park and recorded biodiversity.

Low rubber prices induced these populations to start new and unsustainable activities, like cow ranching, timber cutting, commercial hunting and fishing and animal capturing, as well as fossils and stones trade.

The remaining population, having deep knowledge of the area, may be involved in the Park's surveillance, maintenance and tourism activities.