Sesser is a city in Franklin County, Illinois, United States.

[4] In summer 1904, when coal was discovered at today's Sesser, the area was a prairie covered with wheat and corn fields.

By 1906, the Chicago, Burlington and Quincy Railroad had extended its lines south from Centralia to Sesser, and the new town was named after railroad surveyor John Sesser.

21 mine, by Old Ben Coal Company, was a concern for some local homeowners in the 1980s.

[6] The Sesser Opera House, built in 1914, is listed on the National Register of Historic Places.

25.98% of all households were made up of individuals, and 16.55% had someone living alone who was 65 years of age or older.