Setoperone is a compound that is a ligand to the 5-HT2A receptor.

It can be radiolabeled with the radioisotope fluorine-18 and used as a radioligand with positron emission tomography (PET).

Several research studies have used the radiolabeled setoperone in neuroimaging for the studying neuropsychiatric disorders, such as depression[1] or schizophrenia.

Sn2 alkylation with 4-(4-fluorobenzoyl)piperidine [56346-57-7] (3) under Finkelstein reaction conditions affords setoperone (4).

This drug article relating to the nervous system is a stub.