[1] Mahmudova received her education at the Taskhent Textile Institute, and began her political career with the Young Communist League (Komsomol) in the Soviet era.
Soon after independence, President Islam Karimov named her Minister of Foreign Affairs, at the same time decreeing that Zokir Almatov should become Minister of Internal Affairs.
She did not last long in the position; events during her ministry included the entry of Uzbekistan into the United Nations and a state visit by the President of Turkey.
[3] Otherwise she did not play a major role in the diplomatic life of her country,[4] and during her time at the ministry she kept a relatively low political profile.
[5] Later in her career she became Head of the Department for Attracting Foreign Investments and International Cooperation at the Center for Special Secondary Vocational Education,[2] and also worked at the Ministry of Foreign Affairs.