He won from the Malegaon Central Vidhan Sabha constituency in the 2014 Maharashtra Assembly election.
[4] In 2022, Asif resigned from the Congress Party and joined Sharad Pawar's NCP along with his father Shaikh Rashid.
[5] After the split in the NCP, Asif Shaikh announced to contest the 2024 Maharashtra Assembly Election as Independent.
He however launched a new political party 'Indian Secular Largest Assembly of Maharashtra' or 'I.S.L.A.M.'
on October 20, 2024, also announcing himself to be the candidate of the new party from Malegaon Central assembly seat for the 2024 Maharashtra Vidhan Sabha Polls.