[1] STI is created early during the semiconductor device fabrication process, before transistors are formed.
The key steps of the STI process involve etching a pattern of trenches in the silicon, depositing one or more dielectric materials (such as silicon dioxide) to fill the trenches, and removing the excess dielectric using a technique such as chemical-mechanical planarization.
[2] Certain semiconductor fabrication technologies also include deep trench isolation, a related feature often found in analog integrated circuits.
[4] Basically, due to the electric field enhancement at the edge, it is easier to form a conducting channel (by inversion) at a lower voltage.
[5][6] The main concern for electronic devices is the resulting subthreshold leakage current, which is substantially larger after the threshold voltage reduction.