He was on the team of surgeons who performed the first-ever heart transplant in India at the King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College in Mumbai.

After Panday returned to India from Canada, he joined the King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College (KEM), in which he performed hundreds of open heart surgeries.

Panday, who trained under the Canadian surgeon Wilfred Gordon Bigelow, adopted the technique and tailored it to Indian conditions.

[4][1][5] In 1986 Panday performed a rare heart operation at the Nanavati hospital in Bombay, wherein a large tumor was removed from the left ventricle of a 29-year-old patient.

If the water supply at the hospital failed, he would take a 0.5-inch (13 mm) tubing and connect to the garden tap so everybody could scrub up for surgery.

[7] After retiring from KEM, Panday went into private practice and set up the heart ward at the Nanavati hospital in Mumbai.

On 15 June 1991, the Association of Thoracic and Cardiovascular Surgeons of India was dissolved through a unanimous resolution passed by its general body during its annual meeting in Bombay, and its entire membership, funds, and assets were transferred to the new Association of Cardiovascular-thoracic Surgeons.