Sharp Humor (April 21, 2003 – March 31, 2015) was a Thoroughbred race horse.
Sharp Humor is co-owned by the Purdedel Stable, trained by Dale Romans, and ridden by Mark Guidry.
Sharp Humor was bred in New York by Patrica S. Purdy.
Sharp Humor fractured his knee in the Kentucky Derby and underwent surgery on May 11, 2006 at the Rood & Riddle Equine Hospital in Lexington.
After recovering, he underwent therapeutic swimming at the Kesmark Equine Rehabilitation Center also in Lexington.