Sharptown is a town in Wicomico County, Maryland, United States.

San Domingo School was listed on the National Register of Historic Places in 2007.

The racial makeup of the town was 92.6% White, 5.1% African American, 0.5% Asian, and 1.8% from two or more races.

23.5% of all households were made up of individuals, and 9.6% had someone living alone who was 65 years of age or older.

The racial makeup of the town was 94.92% White, 3.70% African American, 0.15% Asian, and 1.23% from two or more races.

26.0% of all households were made up of individuals, and 14.0% had someone living alone who was 65 years of age or older.