She works alongside NHS clinicians to use tissue engineered skin to benefit patients with burns, chronic ulcers and those recovering from surgery.

[4] In 2004 MacNeil and colleagues developed MySkin, living bandages made from healthy skin cells.

[9] She is part of the University of Leeds Doctoral Training Centre for Tissue Engineering and Regenerative Medicine.

[12] Working with Chris Chapple at the Sheffield Teaching Hospitals NHS Foundation Trust, MacNeil is developing biomaterials to repair tissues in the pelvic floor.

[13][14] She has worked with Wellcome Trust Affordable Healthcare for India programme to develop cell delivery membranes for corneal defects.