[1] On 18 July 2020, as part of the administrative reform of Ukraine, the number of raions of Khmelnytskyi Oblast was reduced to three, and the area of Shepetivka Raion was significantly expanded.

[2][3] The January 2020 estimate of the raion population was 32,100 (2020 est.).

1 urban-type settlement (Hrytsiv) and 68 villages were located in Shepetivka Raion until 2020.

The Homora, Korchyk, Tsvitoha, Smilka and other rivers flow through the district.

After the reform in July 2020, the raion consisted of 18 hromadas:[3] Before the 2020 reform, the raion consisted of four hromadas:[12] From 1923 to 1932, the district was part of the Shepetivka region, then from 1932 to 1937 it was part of the Vinnytsia region.