Dr. Sher Afgan Khan Niazi (Urdu: شیر افگن خان نیازی; died 11 October 2012) was a Pakistani politician.
On 18 February 2008, he lost the general election to an independent candidate, Humair Hayat Khan Rokhri.
On April 8, 2008 he was pelted with rotten eggs and attacked in Lahore, Punjab by the lawyers protesting against his support for dismissing of Supreme Court judges and Lal Masjid operation.
Niazi joined President Pervez Musharraf's newly formed political party, the All Pakistan Muslim League (APML).
His health deteriorated slowly after one of his sons died in car accident in Rawalpindi, and he was diagnosed with Liver cancer in 2012.